You can put in at the dam at Pymatuning and take out at Riverside Park in Greenville.
(about a four-five hour trip)
Put in at Riverside Park in Greenville and take out at Kiddsmill Covered Bridge.
(about a four hour trip)
Put in at Kiddsmill Covered Bridge and take out at Big Bend Access Area at the Shenango Dam. At the 1/2 way point is Hamburg Rd. bridge. Just past that bridge is a fun chute to go through that can be tricky for unexperienced canoeists.
(about a four hour trip)
Put in at Mahany Recreation area (actually turn in just across the bridge by Danny's) and take out at Sharon Tube. (if you get around the dam at the water company somehow, you can go all the way through downtown Sharon and take out at the canoe launch on Budd Street. To do this, you would have to tak out at Sharon Tube, have a vehicle there, drive the canoe to just behind Penn State and put back in)
(about a four hour trip)
Put in at the canoe Launch on Budd Street in Sharon and take out in West Middlesex at the Boat Launch on Campground Rd. (You have to take out the canoe at the low head dam behind Duferco Steel and carry it around the dam on the left hand side)
(about a four hour trip)
Put in at West Middlesex site and take out at Pulaski on rt. 208 (or possibly 108) there is a bridge there.
(about a four hour trip)
Put in in Pulaski and take out at 422 in New Castle.
(a four to five hour trip)
All these trips are unique in their own way. The northern trips are more serene and cleaner. The southern trips are also quite. The trips through Sharon are neat to go behind the mills.